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Formula
C28H36ClN5O3S
MW
558.15
Purity
>90%
Solubility (DMSO Mg/MI)
20
Bio Chemical Notes
LDK378 is potent inhibitor against ALK with IC50 of 0.2 nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively. Phase 2.