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Formula
C18H23BrN2S
MW
379.37
Purity
>97%
Solubility (DMSO Mg/MI)
70
Bio Chemical Notes
Vortioxetine acts as a serotonin transporter blocker (Ki=1.6nM), 5-HT1A receptor agonist (Ki=15 nM), 5-HT1B receptor partial agonist (Ki=33 nM), 5HT3A receptor antagonist (Ki=3.7 nM) and 5HT7 receptor antagonist (Ki=19 nM). Also displays affinity the beta1-adrenergic receptor. Ref: J. Med. Chem. 2011; 54 (9), 3206